WebHere, we report that microRNA-mediated repression of CHROMOMETHYLASE 3 (CMT3) and the chromatin features that CMT3 prefers help prevent ectopic methylation of thousands of genes during embryogenesis that can persist for weeks afterwards. Moreover, CMT3-induced ectopic methylation of genes undergoing transcriptional activation can reduce … WebAug 9, 2016 · Of all known DNA methyltransferases, only CHROMOMETHYLASE 3 (CMT3) is missing from E. salsugineum Identification of an additional angiosperm, Conringia …
Locus-specific control of asymmetric and CpNpG …
WebAug 19, 2024 · CHRO-MOMETHYLASE3 (CMT3) is a plant-specific DNA methyltransferase responsible for cata-lyzing DNA methylation at the CHG (H = A, T, C) context. Here, we identified a positive role of CMT3 in... WebJul 1, 2001 · A genetic screen for suppressors of a hypermethylated clark kent mutant identified nine loss-of-function alleles of CHROMOMETHYLASE3 (CMT3), a novel cytosine methyltransferase homolog. These... parenting month unicef
Natural variation in DNA methylation homeostasis and …
WebDec 10, 2002 · The CMT3 class of genes are specific to the plant kingdom and encode methyltransferase proteins containing a chromo domain . CMT3 loss-of-function mutants were isolated in three independent studies, and … WebMar 17, 2024 · It is now known that the CMT3 protein is involved in a self-reinforcing feedback loop: CMT3 recognizes the histone mark H3K9me2 (histone H3 lysine 9 dimethylation) and then de novo methylates nearby cytosines predominantly in the CHG context but also occasionally in the CG context. WebNov 16, 2024 · Methylation in the CHG (H represents A, C or T) context is maintained by a plant-specific DNA methyltransferase Chromomethylase 3 (CMT3) [9, 10], which often requires methylation of histone H3 at lysine 9 by H3K9 methyltransferases SUVH4/KYP, SUVH5 and SUVH6 ; CMT2 methyltransferase, a homolog of CMT3, was found to … times of india rishabh pant